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VIRALEZE™ targets the area in the nasal cavity where respiratory viruses that cause colds, flu and more severe respiratory illness, such as COVID-19, first attach and start to multiply.

The nasal cavity is the primary site where SARS-CoV-2 (COVID-19) becomes established, before spreading to the lungs.^

VIRALEZE™ contains astodrimer sodium (SPL7013) which is antiviral and has been shown in laboratory studies to inactivate viruses, adding a further physical barrier to respiratory viruses.

^Hou, Y.J., et al. 2020. SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract. Cell 182(2), 429-446.e14. https://doi.org/10.1016/j.cell.2020.05.042
†Paull, J.R.A. et al. Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro (2021). Antiviral Research: https://doi.org/10.1016/j.antiviral.2021.105089.

Astodrimer sodium (SPL7013) acts by blocking the interaction between the SARS-CoV-2 viral “spikes” and the human cells the virus is seeking to infect.

“Spike” proteins on the surface of these (SARS-CoV-2) viruses that come into contact with VIRALEZE™ are trapped by astodrimer sodium. This interaction is “virucidal” – the virus is irreversibly blocked and can no longer infect cells.

This mechanism provides a physical barrier to respiratory viruses in the nasal cavity. The “blocked” viruses are then cleared naturally through the nasal mucus.

†Paull, J.R.A. et al. Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro (2021). Antiviral Research: https://doi.org/10.1016/j.antiviral.2021.105089.

Antiviral activity for astodrimer sodium (SPL7013) proven in laboratory studies.

Astodrimer sodium has demonstrated antiviral activity against a broad spectrum of respiratory viruses in laboratory studies including:

  • SARS-CoV-2 (the coronavirus that causes COVID-19)
  • MERS-CoV (the coronavirus that causes MERS)
  • SARS-CoV (the coronavirus that causes SARS)
  • H1N1 (the influenza virus that caused Swine Flu)
  • H3N2 (the influenza virus that caused Avian Flu)
  • RSV (respiratory syncytial virus)

Astodrimer sodium (SPL7013) has been shown to be virucidal, inactivating >99.9% of SARS-CoV-2 within one minute.

† Paull, J.R.A. et al. Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro (2021). Antiviral Research: https://doi.org/10.1016/j.antiviral.2021.105089.

Liên hệ mua VIRALEZE hôm nay. 090.3739.488

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